EFFECTS OF DIETARY RESTRICTION ON AGE-ASSOCIATED PATHOLOGIC CHANGES IN F-344 RATS
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چکیده
منابع مشابه
Effects of a Combination of Dietary Restriction and Exercise Training on Myocardial Apoptosis in Male Rats
Background and Objectives: Apoptosis plays a key role in pathogenesis of various cardiovascular diseases due to loss of terminally differentiated cardiac myocytes. Therefore, the aim of this study was to investigate effects of combined dietary restriction and aerobic training on indices of myocardial apoptosis in male rats. Materials and Methods: In this study, 32 three-month-old male rats wer...
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Aging is associated with left ventricular hypertrophy, dilatation, and fibrosis of the heart. The Fischer 344/Brown Norway F1 (F344/BNF1) rat is recommended for age-related studies by the National Institutes on Aging because this hybrid rat lives longer and has a lower rate of pathological conditions than inbred rats. However, little is known about age-associated changes in cardiac and aortic f...
متن کاملEffects of dietary restriction on cellular immunity in rats.
Phagocytosis of opsonized sheep red blood cells (SRBC) by alveolar macrophages (AM) was measured in rats fasted for 1 to 9 days or fed on diets restricted 20 to 95% compared to control group for 2 and 8 weeks. In rats fasted for 1 to 6 days, AM showed an increased phagocytosis at 2 days after fasting, but their phagocytic activity remarkably decreased afterwards. Furthermore, phagocytic activit...
متن کاملEffects of age and caloric restriction on cell proliferation in hepatocyte cultures from control and hepatectomized Fischer 344 rats.
The effects of age and caloric restriction on cell proliferation, measured as scheduled DNA synthesis (SDS), were evaluated in primary hepatocyte cultures from control and partially hepatectomized (PH) young to old ad libitum (AL) and caloric-restricted (CR) male Fischer 344 (F344) rats. We reported significant age- or CR-related decreases in SDS in control cultures. PH-induced cultures exhibit...
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ژورنال
عنوان ژورنال: Journal of Toxicologic Pathology
سال: 1990
ISSN: 0914-9198,1881-915X
DOI: 10.1293/tox.3.209